Treatment outcomes of patients with primary squamous cell carcinoma of the retromolar trigone

Objectives/Hypothesis Squamous cell carcinoma of the retromolar trigone (RMT SCC) is a relatively uncommon primary site for oral cavity malignancy. However, given its proximity to the mandible and buccal mucosa, RMT SCC typically exhibits early invasion and generally presents at an advanced stage. Large‐sample studies are needed to assess the epidemiology and clinical outcomes of this tumor. Our aim was to describe the determinants of survival in patients with RMT SCC. Study Design Retrospective cohort study. Methods Retrospective, population‐based cohort study of patients in the Surveillance, Epidemiology, and End Results tumor registry who were diagnosed with RMT SCC from 1973 to 2012. Primary endpoints were overall survival (OS) and disease‐specific survival (DSS). Results A total of 4,022 cases of RMT SCC were identified. The mean age at diagnosis was 65 years. Thirty‐nine percent of cases presented with stage IV disease. The median OS by stages I to IV were 73.7, 52.4, 27.5, and 23.4 months, respectively (P