Chronic subdural hematoma in patients aged 80 years and older: A two-centre study

•Patients over 80 with chronic subdural hematoma are more and more very frequent in daily practice.•Risk factors influencing outcome of surgery have been analysed in 151 surgically treated patients.•Higher CCI correlated with complications (OR = 3,18) and 6-month mortality (OR = 11,71).•Patients under antithrombotic drugs had a longer hospital stay (OR = 3,07).•CCI can represent a useful tool to predict outcome after surgery for CSDH in very elderly patients. Chronic subdural hematoma (CSDH) is a common condition in the elderly, and the ageing of population will increase the number of “superaged” patients presenting this pathology for the years to come. Few studies investigating the outcome of superaged patients surgically treated for CSDH are available, and study populations are generally small. The outcome of surgically treated patients and risk factors are not completely clear. Aim of the work is to identify the risk factors which may influence the outcome of patients aged 80 years and older surgically treated for CSDH. This is a retrospective two-centre study including 151 surgically treated patients. A univariate (Fisher exact test) and multivariate (logistic regression) analysis of possible risk factors influencing outcome was performed. Outcome was expressed as: 6-month clinical outcome, 6-month mortality, complications and length of hospital stay. Univariate analysis showed an association between Charlson Comorbidity Index (CCI) and 6-month clinical outcome (p = 0,048), complications (p = 0,034) and 6-month mortality (p = 0,007). Antithrombotic drugs were associated with longer hospital stay (p