Clonal Hematopoiesis: A new layer in the liquid biopsy story in lung cancer
Cell free DNA (cfDNA) is a unique biospecimen that contains multiple sources of DNA including tumor, germline, fetal, and others. Clonal hematopoiesis, a process that leads to expansion of mutations in peripheral blood cells, is an additional source of DNA that adds a layer of complexity when interp...
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| Veröffentlicht in: | Clinical cancer research 2018-09, Vol.24 (18), p.4352-4354 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Cell free DNA (cfDNA) is a unique biospecimen that contains multiple sources of DNA including tumor, germline, fetal, and others. Clonal hematopoiesis, a process that leads to expansion of mutations in peripheral blood cells, is an additional source of DNA that adds a layer of complexity when interpreting results. |
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| ISSN: | 1078-0432 1557-3265 |
| DOI: | 10.1158/1078-0432.CCR-18-0969 |