Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery

Patients undergoing major abdominal surgery received restrictive or liberal intravenous fluids during surgery and up to 24 hours thereafter. The restrictive regimen did not improve disability-free survival and resulted in increased acute kidney injury.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2018-06, Vol.378 (24), p.2263-2274
Hauptverfasser:	Myles, Paul S, Bellomo, Rinaldo, Corcoran, Tomas, Forbes, Andrew, Peyton, Philip, Story, David, Christophi, Chris, Leslie, Kate, McGuinness, Shay, Parke, Rachael, Serpell, Jonathan, Chan, Matthew T.V, Painter, Thomas, McCluskey, Stuart, Minto, Gary, Wallace, Sophie
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Abdomen - surgery Abdominal surgery Acute Kidney Injury - etiology Aged Anesthesia Blood Loss, Surgical Death Design Digestive System Surgical Procedures - adverse effects Digestive System Surgical Procedures - mortality Drug dosages Female Fluid intake Fluid Therapy - adverse effects Fluid Therapy - methods Fluids Follow-Up Studies Hospitals Humans Hypotonic Solutions - administration & dosage Hypotonic Solutions - adverse effects Intravenous administration Kidneys Laparoscopy Male Medical research Middle Aged Perfusion Postoperative Complications - epidemiology Postoperative Complications - prevention & control Rehydration Solutions - administration & dosage Rehydration Solutions - adverse effects Rehydration Solutions - chemistry Risk Factors Surgery Surgical site infections Survival Systemic diseases
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Patients undergoing major abdominal surgery received restrictive or liberal intravenous fluids during surgery and up to 24 hours thereafter. The restrictive regimen did not improve disability-free survival and resulted in increased acute kidney injury.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa1801601