Phase sensitive reconstruction of T1-weighted inversion recovery in the evaluation of the cervical cord lesions in Multiple Sclerosis; is it similarly eligible in 1.5 T magnet fields?

•In 3 T MRI, PSIR may depict the cervical MS lesions better than STIR.•In 1.5 T MRI, STIR significantly has a superiority over PSIR reconstructions.•Superiority of STIR in 1.5 T is both in detection rate and in illustrating the margins. In primary studies with 3 T Magnets, phase sensitive reconstruc...

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Veröffentlicht in:Multiple sclerosis and related disorders 2018-07, Vol.23, p.17-22
Hauptverfasser: Shayganfar, A., Sarrami, A.H., Fathi, S., Shaygannejad, V., Shamsian, S.
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Sprache:eng
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Zusammenfassung:•In 3 T MRI, PSIR may depict the cervical MS lesions better than STIR.•In 1.5 T MRI, STIR significantly has a superiority over PSIR reconstructions.•Superiority of STIR in 1.5 T is both in detection rate and in illustrating the margins. In primary studies with 3 T Magnets, phase sensitive reconstruction of T1-weighted inversion recovery (PSIR) have showed ability to depict the cervical multiple sclerosis (MS) lesions some of which may not be detected by short tau inversion recovery (STIR). Regarding to more availability of 1.5 T MRI, this study was designed to evaluate the eligibility of PSIR in 1.5 T for detection of spinal cord MS lesions. In a study between September 2016 till March 2017 the patients with proven diagnosis of MS enrolled to the study. The standard protocol (sagittal STIR and T2W FSE and axial T2W FSE) as well as sagittal PSIR sequences were performed using a 1.5 T magnet. The images were studied and the lesions were localized and recorded as sharp or faint on each sequence. Of 25 patients (22 females and 3 males, with mean age of 33.5 ± 9.8 years and mean disease duration of 5.4 ± 3.9 years) 69 lesions in STIR, 53 lesions in T2W FSE, 47 lesions in Magnitude reconstruction of PSIR (Magnitude), and 30 lesions in phase sensitive (real) reconstruction PSIR were detected. A Wilcoxon signed-rank test showed STIR has a statistically significant higher detection rate of the plaques rather than other three sequences. (STIR and T2W FSE, Z = −4.000, p 
ISSN:2211-0348
2211-0356
DOI:10.1016/j.msard.2018.04.013