Can we assess severity of Guillain‐Barré syndrome using absolute monocyte count?
Introduction Guillain‐Barré syndrome (GBS) is an inflammatory demyelinating autoimmune disease, associated with blood‐nerve barrier breakdown, inflammatory cells infiltration, and cytokine leakage in the peripheral nervous system. Currently, it has been revealed that monocytes play key roles in the...
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Veröffentlicht in: | International journal of laboratory hematology 2018-08, Vol.40 (4), p.488-492 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Introduction
Guillain‐Barré syndrome (GBS) is an inflammatory demyelinating autoimmune disease, associated with blood‐nerve barrier breakdown, inflammatory cells infiltration, and cytokine leakage in the peripheral nervous system. Currently, it has been revealed that monocytes play key roles in the inflammatory response. Therefore, we aimed to assess the correlation between monocyte count and GBS in this study.
Methods
Retrospective study was conducted in 114 patients with GBS and 120 age‐ and gender‐matched individuals.
Results
Absolute monocyte count in patients with GBS was higher than that in healthy controls (0.61 ± 0.24 vs 0.41 ± 0.10; P |
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ISSN: | 1751-5521 1751-553X |
DOI: | 10.1111/ijlh.12845 |