Can we assess severity of Guillain‐Barré syndrome using absolute monocyte count?

Introduction Guillain‐Barré syndrome (GBS) is an inflammatory demyelinating autoimmune disease, associated with blood‐nerve barrier breakdown, inflammatory cells infiltration, and cytokine leakage in the peripheral nervous system. Currently, it has been revealed that monocytes play key roles in the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International journal of laboratory hematology 2018-08, Vol.40 (4), p.488-492
Hauptverfasser: Li, X., Li, W., Luo, Y., Qin, L., Su, Q., Mo, W.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Introduction Guillain‐Barré syndrome (GBS) is an inflammatory demyelinating autoimmune disease, associated with blood‐nerve barrier breakdown, inflammatory cells infiltration, and cytokine leakage in the peripheral nervous system. Currently, it has been revealed that monocytes play key roles in the inflammatory response. Therefore, we aimed to assess the correlation between monocyte count and GBS in this study. Methods Retrospective study was conducted in 114 patients with GBS and 120 age‐ and gender‐matched individuals. Results Absolute monocyte count in patients with GBS was higher than that in healthy controls (0.61 ± 0.24 vs 0.41 ± 0.10; P  
ISSN:1751-5521
1751-553X
DOI:10.1111/ijlh.12845