Gold Glyconanoparticles as Water-Soluble Polyvalent Models To Study Carbohydrate Interactions

Gold Glyconanoparticles as Water-Soluble Polyvalent Models To Study Carbohydrate Interactions

Glycosphingolipid clustering and interactions at the cell membrane can be modeled by gold glyconanoparticles prepared with biologically significant oligosaccharides. Such water‐soluble gold glyconanoparticles with highly polyvalent carbohydrate displays (see picture, gray hemisphere: gold nanopartic...

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Veröffentlicht in:Angewandte Chemie International Edition 2001-06, Vol.40 (12), p.2257-2261
Hauptverfasser: de la Fuente, Jesús M., Barrientos, Africa G., Rojas, Teresa C., Rojo, Javier, Cañada, Javier, Fernández, Asunción, Penadés, Soledad
Format: Artikel
Sprache:eng
Schlagworte:
carbohydrates
glycolipids
gold
nanoparticles
self-assembly
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Zusammenfassung:Glycosphingolipid clustering and interactions at the cell membrane can be modeled by gold glyconanoparticles prepared with biologically significant oligosaccharides. Such water‐soluble gold glyconanoparticles with highly polyvalent carbohydrate displays (see picture, gray hemisphere: gold nanoparticle) have been obtained by a simple and versatile strategy.
ISSN:1433-7851
1521-3773
DOI:10.1002/1521-3773(20010618)40:12<2257::AID-ANIE2257>3.0.CO;2-S