Organic Synthesis and Biological Signal Transduction

Organic Synthesis and Biological Signal Transduction

The understanding of cellular communication pathways in molecular detail is an important goal of bioorganic research. The synthesis of analogues of active substances (e.g. 1) to study the regulation of muscle contraction or the specific lipid modification of representative peptides (→2) to investiga...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie International Edition 1998-04, Vol.37 (6), p.688-749
Hauptverfasser: Hinterding, Klaus, Alonso-Díaz, Daniel, Waldmann, Herbert
Format: Artikel
Sprache:eng
Schlagworte:
Bioorganic chemistry
Enzyme inhibitors
Peptide conjugates
Signal transduction
Synthetic methods
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The understanding of cellular communication pathways in molecular detail is an important goal of bioorganic research. The synthesis of analogues of active substances (e.g. 1) to study the regulation of muscle contraction or the specific lipid modification of representative peptides (→2) to investigate their subcellular, targeted transfer to intracellular membranes are examples of the capability of organic synthesis is in the research of biological signal transduction mechanisms.
ISSN:1433-7851
1521-3773
DOI:10.1002/(SICI)1521-3773(19980403)37:6<688::AID-ANIE688>3.0.CO;2-B