FT-IR Mapping-A New Tool for Spatially Resolved Characterization of Polymer-Bound Combinatorial Compound Libraries with IR Microscopy

FT-IR Mapping-A New Tool for Spatially Resolved Characterization of Polymer-Bound Combinatorial Compound Libraries with IR Microscopy

In the search for selective receptors, a promising approach is provided by immobilization of cyclopeptides on sensor surfaces (see picture) and subsequent detection of low molecular weight analytes with reflectometric interference spectroscopy (RIfS). Together with combinatorial chemistry, this inno...

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Veröffentlicht in:Angewandte Chemie International Edition 1998-12, Vol.37 (23), p.3311-3314
Hauptverfasser: Haap, Wolfgang J., Walk, Tilmann B., Jung, Günther
Format: Artikel
Sprache:eng
Schlagworte:
Combinatorial chemistry
IR spectroscopy
Microscopy
Solid-phase syntheses
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Beschreibung
Zusammenfassung:In the search for selective receptors, a promising approach is provided by immobilization of cyclopeptides on sensor surfaces (see picture) and subsequent detection of low molecular weight analytes with reflectometric interference spectroscopy (RIfS). Together with combinatorial chemistry, this innovative method offers a great potential for applications as sensors.
ISSN:1433-7851
1521-3773
DOI:10.1002/(SICI)1521-3773(19981217)37:23<3311::AID-ANIE3311>3.0.CO;2-2