New metabolites, sarcopodinols A and B, isolated from deep-sea derived fungal strain Sarcopodium sp. FKJ-0025

Fungal strain FKJ-0025 was isolated from deep-sea sediment collected at the Wakamiko Caldera in Kagoshima Bay (water depth: 200 m). The fungal strain FKJ-0025 was identified as the genus Sarcopodium based on its morphology and internal transcribed spacer (ITS) sequence. Two new compounds, designated...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2018-08, Vol.82 (8), p.1323-1326
Hauptverfasser:	Matsuo, Hirotaka, Nonaka, Kenichi, Nagano, Yuriko, Yabuki, Akinori, Fujikura, Katsunori, Takahashi, Yōko, Ōmura, Satoshi, Nakashima, Takuji
Format:	Artikel
Sprache:	eng
Schlagworte:	Absolute configuration anti-tumor Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Aquatic Organisms - metabolism Cell Line, Tumor Chromatography, Liquid deep-sea derived fungus Drug Screening Assays, Antitumor Fermentation Geologic Sediments - microbiology Humans Hypocreales - metabolism Mass Spectrometry Molecular Structure PC screening Polyphenols - chemistry Polyphenols - isolation & purification Polyphenols - pharmacology Seawater Secondary Metabolism Spectrophotometry, Ultraviolet
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Beschreibung
Zusammenfassung:	Fungal strain FKJ-0025 was isolated from deep-sea sediment collected at the Wakamiko Caldera in Kagoshima Bay (water depth: 200 m). The fungal strain FKJ-0025 was identified as the genus Sarcopodium based on its morphology and internal transcribed spacer (ITS) sequence. Two new compounds, designated sarcopodinols A (1) and B (2), were isolated together with the known compound SF-227 (3).
ISSN:	0916-8451 1347-6947
DOI:	10.1080/09168451.2018.1467264