Photoredox‐Catalyzed Decarboxylative Oxidation of Arylacetic Acids

A photoredox‐catalyzed decarboxylative oxidation of arylacetic acids, which are privileged scaffolds in pharmaceuticals, is reported herein. The established method is operationally simple and a variety of substrates are applicable, providing rapid access to dehomologated bioisosteres of common pharmaceuticals. Bio products: Derivatization of potentially bioactive compounds plays an important role in the fields of drug discovery and chemical biology. Herein, a photoredox‐catalyzed decarboxylative oxidation of arylacetic acids is described. The established method is operationally simple and a variety of substrates are tolerated, providing rapid access to dehomologated bioisosteres of common pharmaceuticals.