Azithromycin to Reduce Childhood Mortality in Sub-Saharan Africa

Childhood mortality remains high in sub-Saharan Africa. In this cluster-randomized, placebo-controlled trial, mortality among children younger than 5 years of age was lower among those who received azithromycin than among those who received placebo.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2018-04, Vol.378 (17), p.1583-1592
Hauptverfasser:	Keenan, Jeremy D, Bailey, Robin L, West, Sheila K, Arzika, Ahmed M, Hart, John, Weaver, Jerusha, Kalua, Khumbo, Mrango, Zakayo, Ray, Kathryn J, Cook, Catherine, Lebas, Elodie, O’Brien, Kieran S, Emerson, Paul M, Porco, Travis C, Lietman, Thomas M
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Anti-Bacterial Agents - therapeutic use Antibiotic resistance Antibiotics Azithromycin Azithromycin - therapeutic use Body weight Child mortality Child Mortality - trends Child, Preschool Childhood Children Communicable Disease Control Communicable Diseases - mortality Confidence intervals Drug Resistance, Bacterial Female Humans Infant Infant Mortality - trends Intervention Malawi - epidemiology Male Mass Drug Administration - mortality Maternal & child health Mortality Niger - epidemiology Preschool children Public Health Streptococcus infections Sustainable development Tanzania - epidemiology
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Beschreibung
Zusammenfassung:	Childhood mortality remains high in sub-Saharan Africa. In this cluster-randomized, placebo-controlled trial, mortality among children younger than 5 years of age was lower among those who received azithromycin than among those who received placebo.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa1715474