miR-375 prevents nasal mucosa cells from apoptosis and ameliorates allergic rhinitis via inhibiting JAK2/STAT3 pathway

[Display omitted] •A new critical role of miR-375 in allergic rhinitis is proposed.•The mechanisms of miR-375 in allergic rhinitis were further studied.•miR-375/JAK2/STAT3 regulatory axis was firstly identified in nasal mucosa cells.•The novel mechanism provides new potential targets for allergic rh...

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Veröffentlicht in:Biomedicine & pharmacotherapy 2018-07, Vol.103, p.621-627
Hauptverfasser: Wang, Tao, Chen, Dong, Wang, Peihua, Xu, Zhou, Li, Ying
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Sprache:eng
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