Recombinant human granulocyte-macrophage colony-stimulating factor: effect of glycosylation on pharmacokinetic parameters

The pharmacokinetic behaviour of the non-glycosylated, bacterially-derived recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) and the glycosylated mammalian product was studied after intra and extra vascular administration of a single dose in rodents. Each route of adminis...

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Veröffentlicht in:	Electronic Journal of Biotechnology 2007-04, Vol.10 (2)
Hauptverfasser:	Marini, Guillermo, Forno, Guillermina, Kratje, Ricardo, Etcheverrigaray, Marina
Format:	Artikel
Sprache:	eng
Schlagworte:	glycosylation, pharmacokinetic parameters, rhGM-CSF
Online-Zugang:	Volltext
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