Two long non‐coding RNAs, Prcat17.3 and Prcat38, could efficiently discriminate benign prostate hyperplasia from prostate cancer

Background Long non‐coding RNAs (lncRNAs) have recently appeared as new players in cancer biology. Recently, a number of new prostate cancer‐associated lncRNAs has been listed via RNA‐seq approach by Mitranscriptome project. By analyzing this data we chose four lncRNAs (Prcat17.3, Prcat38, Prcat47, and Cat2184.4) and evaluated their expressions and their abilities to discriminate prostate tumors from benign prostate hyperplasia (BPH). Methods Fresh Prostate tissue samples (30 BPH, and 30 tumor samples) and urine samples (19 BPH, and 19 tumor samples) were collected and their total RNA extracted for cDNA syntheses. The expression of candidate lncRNAs was assessed by the real‐time PCR technique. Results Our data revealed that the expression levels of PRCAT17.3 (P