Daclatasvir and Sofosbuvir With or Without Ribavirin in Liver Transplant Recipients: A Single-Center Real-World Study

Treatment with direct-acting antiviral drugs in interferon-free regimens is currently recommended for viral hepatitis C recurrence after liver transplantation. There are limited data regarding its results in this population, and no optimal treatment scheme has yet been singled out. We report our rea...

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Veröffentlicht in:Transplantation proceedings 2018-04, Vol.50 (3), p.769-771
Hauptverfasser: Mucenic, M., Bandeira de Mello Brandao, A., Marroni, C.A., Medeiros Fleck, A., Zanotelli, M.L., Kiss, G., Meine, M.H., Leipnitz, I., Soares Schlindwein, E., Martini, J., Costabeber, A.M., Sacco, F.K.F., Cracco Cantisani, G.P.
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Sprache:eng
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Zusammenfassung:Treatment with direct-acting antiviral drugs in interferon-free regimens is currently recommended for viral hepatitis C recurrence after liver transplantation. There are limited data regarding its results in this population, and no optimal treatment scheme has yet been singled out. We report our real-world results in liver transplant (LT) recipients. All patients were hepatitis C virus (HCV) monoinfected and completed a 12-week treatment course, followed 12 weeks later by HCV polymerase chain reaction testing with 12 IU/mL sensibility. Liver fibrosis was graded with the use of biopsies taken 
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2018.02.001