Hepatitis D infection in Brazil: Prevalence and geographical distribution of anti‐Delta antibody

In Brazil, the Amazon Basin is endemic for hepatitis D virus (HDV) infection; however, studies in other regions of the country are scarce. This study aims to map the seroepidemiological situation of anti‐Delta antibodies in chronic hepatitis B carriers in all five Brazilian geographic regions. Serum...

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Veröffentlicht in:	Journal of medical virology 2018-08, Vol.90 (8), p.1358-1363
Hauptverfasser:	Lago, Barbara V., Mello, Francisco C. A., Barros, Tairine M., Mello, Vinicius M., Villar, Livia M., Lewis‐Ximenez, Lia L., Pardini, Maria Inês M. C., Lampe, Elisabeth
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Antibodies Brazil Disease control Epidemiology Geographical distribution HDV Hepatitis Hepatitis B Hepatitis B surface antigen Immunoassay Immunoglobulins Infections River basins Seroepidemiology Virology Viruses
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Zusammenfassung:	In Brazil, the Amazon Basin is endemic for hepatitis D virus (HDV) infection; however, studies in other regions of the country are scarce. This study aims to map the seroepidemiological situation of anti‐Delta antibodies in chronic hepatitis B carriers in all five Brazilian geographic regions. Serum samples from 1240 HBsAg positive individuals (55.4% men; mean age 43.1 ± 13.4 years) from 24 of 26 Brazilian states were tested for the presence of anti‐Delta antibodies using a commercial immunoassay. Anti‐Delta antibodies were detected in 40 samples (3.2%; 52.5% female; mean age of 38.1 ± 13.8 years). Age less than 20 years was significantly associated with anti‐HDV positivity (P
ISSN:	0146-6615 1096-9071
DOI:	10.1002/jmv.25196