Insulin resistance and metabolic syndrome criteria in lean, normoglycemic college-age subjects

Insulin resistance and metabolic syndrome criteria in lean, normoglycemic college-age subjects

The goal of this study was to determine insulin sensitivity in a fasted state and during an oral glucose tolerance test (OGTT), in normoglycemic (NGT), lean (L) (n = 35) and, for comparison, overweight/obese (OW/O) (n = 9) college-aged subjects. Insulin sensitivity for 44 NGT, normotensive subjects,...

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Veröffentlicht in:Diabetes & metabolic syndrome clinical research & reviews 2018-09, Vol.12 (5), p.609-616
Hauptverfasser: Townsend, Dana K., McGregor, Katheryn, Wu, Esther, Cialkowski, Kathryn, Haub, Mark D., Barstow, Thomas J.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Blood Glucose - metabolism
Body Mass Index
College-age
Female
Glucose Tolerance Test - methods
Glycemic Index - physiology
Humans
Hyperinsulinemia
Insulin resistance
Insulin Resistance - physiology
Male
Metabolic syndrome
Metabolic Syndrome - blood
Metabolic Syndrome - diagnosis
Normoglycemia
Students
Thinness - blood
Thinness - diagnosis
Universities
Young Adult
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Zusammenfassung:The goal of this study was to determine insulin sensitivity in a fasted state and during an oral glucose tolerance test (OGTT), in normoglycemic (NGT), lean (L) (n = 35) and, for comparison, overweight/obese (OW/O) (n = 9) college-aged subjects. Insulin sensitivity for 44 NGT, normotensive subjects, age 18–26 yrs., was determined by homeostasis model assessment (HOMA-IR) and from Matsuda index (ISI Matsuda). Subjects were normoglycemic fasted (4.59 + 0.35 mmol/L) and at two hours post OGTT (4.52  + 1.35 mmol/L). Besides anthropometric measures, there were significant differences between OW/O and L for fasting insulin (P 
ISSN:1871-4021
1878-0334
DOI:10.1016/j.dsx.2018.03.025