International, multicenter evaluation of a new D-dimer assay for the exclusion of venous thromboembolism using standard and age-adjusted cut-offs

We sought to determine the test characteristics of an automated INNOVANCE D-dimer assay for the exclusion of pulmonary embolism (PE) and deep venous thrombosis (DVT) in emergency department (ED) patients using standard and age-adjusted cut-offs. Cross-sectional, international, multicenter study of c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Thrombosis research 2018-06, Vol.166, p.63-70
Hauptverfasser:	Parry, Blair Alden, Chang, Anna Marie, Schellong, Sebastian M., House, Stacey L., Fermann, Gregory J., Deadmon, Erin K., Giordano, Nicholas J., Chang, Yuchiao, Cohen, Jason, Robak, Nancy, Singer, Adam J., Mulrow, Mary, Reibling, Ellen T., Francis, Samuel, Griffin, S. Michelle, Prochaska, Jürgen H., Davis, Barbara, McNelis, Patricia, Delgado, Joao, Kümpers, Philipp, Werner, Nikos, Gentile, Nina T., Zeserson, Eli, Wild, Philipp S., Limkakeng, Alexander T., Walters, Elizabeth Lea, LoVecchio, Frank, Theodoro, Daniel, Hollander, Judd E., Kabrhel, Christopher
Format:	Artikel
Sprache:	eng
Schlagworte:	Age-adjustment D-dimer Deep vein thrombosis Emergency department Pulmonary embolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	We sought to determine the test characteristics of an automated INNOVANCE D-dimer assay for the exclusion of pulmonary embolism (PE) and deep venous thrombosis (DVT) in emergency department (ED) patients using standard and age-adjusted cut-offs. Cross-sectional, international, multicenter study of consecutive patients with suspected DVT or PE in 24 centers (18 USA, 6 Europe). Evaluated patients had low or intermediate Wells PE or DVT scores. For the standard cut-off, a D-dimer result
ISSN:	0049-3848 1879-2472
DOI:	10.1016/j.thromres.2018.04.003