Association between serum uric acid, high sensitive C‐reactive protein and pro‐oxidant‐antioxidant balance in patients with metabolic syndrome

There is persuasive evidence that oxidative stress and inflammation are features of the metabolic syndrome (MetS). We have investigated the relationship between serum pro‐oxidant‐antioxidant balance (PAB), serum uric acid, and high sensitive C‐reactive protein (hs‐CRP) in 7,208 participants from the MASHAD study cohort, who were categorized as having MetS, or not, using International Diabetes Foundation (IDF) criteria. Serum hs‐CRP was measured by Polyethylene glycol (PEG)‐enhanced immunoturbidimetry method using an Alycon analyzer (ABBOTT, Chicago, IL, USA). A colorimetric method was used to determine serum PAB. Serum PAB values were significantly higher in the individuals with MetS compared to those without (P