Structure and Functions of the Mediator Complex

Mediator is a key factor in the regulation of expression of RNA polymerase II-transcribed genes. Recent studies have shown that Mediator acts as a coordinator of transcription activation and participates in maintaining chromatin architecture in the cell nucleus. In this review, we present current co...

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Veröffentlicht in:	Biochemistry (Moscow) 2018-04, Vol.83 (4), p.423-436
Hauptverfasser:	Putlyaev, E. V., Ibragimov, A. N., Lebedeva, L. A., Georgiev, P. G., Shidlovskii, Y. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Chromatin DNA-directed RNA polymerase Gene expression Genetic aspects Genetic regulation Genetic research Life Sciences Microbiology Nuclei Nuclei (cytology) Proteins Review Ribonucleic acid RNA RNA polymerase RNA polymerase II RNA polymerases Transcription activation
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