Micromagnetic selection of aptamers in microfluidic channels

Aptamers are nucleic acid molecules that have been selected in vitro to bind to their molecular targets with high affinity and specificity. Typically, the systematic evolution of ligands by exponential enrichment (SELEX) process is used for the isolation of specific, high-affinity aptamers. SELEX, h...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2009-03, Vol.106 (9), p.2989-2994
Hauptverfasser: Lou, Xinhui, Qian, Jiangrong, Xiao, Yi, Viel, Lisan, Gerdon, Aren E, Lagally, Eric T, Atzberger, Paul, Tarasow, Theodore M, Heeger, Alan J, Soh, H. Tom
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Sprache:eng
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