New alkaloids and diterpenes from a deep ocean sediment derived fungus Penicillium sp

New alkaloids and diterpenes from a deep ocean sediment derived fungus Penicillium sp

Four new alkaloids, including two new meleagrin analogs, meleagrins B ( 2) and C ( 3), and two new diketopiperazines, roquefortines F ( 5) and G ( 6), together with six new diterpenes, conidiogenones B–G ( 7– 12), were isolated from a deep ocean sediment derived fungus Penicillium sp. The structures...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Tetrahedron 2009-01, Vol.65 (5), p.1033-1039
Hauptverfasser: Du, Lin, Li, Dehai, Zhu, Tianjiao, Cai, Shengxin, Wang, Fengping, Xiao, Xiang, Gu, Qianqun
Format: Artikel
Sprache:eng
Schlagworte:
Alicyclic compounds, terpenoids, prostaglandins, steroids
Alkaloid
Chemistry
Deep ocean
Diterpene
Exact sciences and technology
Fungus
Organic chemistry
Penicillium
Penicillium sp
Peptides
Preparations and properties
Terpenoids
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Four new alkaloids, including two new meleagrin analogs, meleagrins B ( 2) and C ( 3), and two new diketopiperazines, roquefortines F ( 5) and G ( 6), together with six new diterpenes, conidiogenones B–G ( 7– 12), were isolated from a deep ocean sediment derived fungus Penicillium sp. The structures and stereochemistry of the new compounds were elucidated by spectroscopic methods. The cytotoxicity of the new compounds against the HL-60, A-549, BEL-7402, and MOLT-4 cell lines was evaluated. [Display omitted]
ISSN:0040-4020
1464-5416
DOI:10.1016/j.tet.2008.11.078