Why validation of prognostic models matters?

Why validation of prognostic models matters?

Prognostic models are powerful tools for treatment personalisation. However, not all proposed models work well when validated using new data, despite impressive results being reported initially. Here, we will use a hands-on approach to highlight important aspects of prognostic modelling, as well as...

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Veröffentlicht in:Radiotherapy and oncology 2018-06, Vol.127 (3), p.370-373
Hauptverfasser: Zwanenburg, Alex, Löck, Steffen
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
Prognostic models
TRIPOD
Validation
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container_title Radiotherapy and oncology
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creator Zwanenburg, Alex
Löck, Steffen
description Prognostic models are powerful tools for treatment personalisation. However, not all proposed models work well when validated using new data, despite impressive results being reported initially. Here, we will use a hands-on approach to highlight important aspects of prognostic modelling, as well as to demonstrate methods to generate generalisable models.
doi_str_mv 10.1016/j.radonc.2018.03.004
format Article
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identifier ISSN: 0167-8140
ispartof Radiotherapy and oncology, 2018-06, Vol.127 (3), p.370-373
issn 0167-8140
1879-0887
language eng
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source Elsevier ScienceDirect Journals
subjects Biomarkers
Prognostic models
TRIPOD
Validation
title Why validation of prognostic models matters?
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