Phytochemical and antifungal studies on Terminalia mollis and Terminalia brachystemma

Phytochemical investigation of the stem bark of Terminalia mollis afforded friedelin ( 1), catechin with epicatechin (2), gallocatechin with epigallocatechin (3) and 3- O-methylellagic acid 4'- O-α-rhamnopyranoside (4). Arjunolic acid with 2α, 3β, 23-trihydroxy-urs-12-en-28-oic acid ( 5), 2α-hydroxyursolic acid (6), gallic acid (7), chebulanin ( 8) and 2''- O-galloylvitexin ( 9) were isolated from the leaf. Chebulanin (8), betulinic acid ( 10), ursolic acid ( 11), catechin ( 12), isoorientin ( 13), orientin (14), isovitexin (15) and punicalagin ( 16) were isolated from Terminalia brachystemma leaf. The first full unambiguous NMR assignments for ( 4) and ( 8), and revised assignments for ( 9), are reported. Compound (16) showed good activity against three Candida species. [Display omitted]