Graded exercise self-help for chronic fatigue syndrome in GETSET

According to the GES Therapist Manual “a central concept of GET and GES is to maintain exercise as much as possible during a CFS/ME [chronic fatigue syndrome/myalgic encephalomyelitis] setback.” 5 More adherence data could help investigate whether the lower rates of harm found in research studies are due to patients not complying with this central concept and instead using pacing, which has been associated with a lower rate of harm in surveys.4 I declare no competing interests. 1 JP Ioannidis, SJ Evans, PC Gøtzsche, Better reporting of harms in randomized trials: an extension of the CONSORT statement, Ann Intern Med, Vol. 141, 2004, 781-788 2 LV Clark, F Pesola, JM Thomas, M Vergara-Williamson, M Beynon, PD White, Guided graded exercise self-help plus specialist medical care versus specialist medical care alone for chronic fatigue syndrome (GETSET): a pragmatic randomised controlled trial, Lancet, Vol. 390, 2017, 363-373 3 LV Clark, P McCrone, D Ridge, Graded exercise therapy guided self-help trial for patients with chronic fatigue syndrome (GETSET): protocol for a randomized controlled trial and interview study, JMIR Res Protoc, Vol. 5, 2016, e70 4 T Kindlon, Bull IACFS ME, Vol. 19, 2011, 59-111 5 LV Clark, E Tims, PD White, (accessed June 29, 2017).