Omeprazole‐induced hypertrichosis in two children

Omeprazole‐induced hypertrichosis in two children

Omeprazole significantly increases duodenal prostaglandin E2 synthesis. Prostaglandins are involved in hair growth regulation: prostaglandin E2 and prostaglandin F2 alpha stimulate hair growth, and prostaglandin D2 has an inhibitory effect. The use of omeprazole can cause acquired generalized hypert...

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Veröffentlicht in:Pediatric dermatology 2018-07, Vol.35 (4), p.e212-e214
Hauptverfasser: Elosua‐González, Marta, Campos‐Domínguez, Minia, Bancalari, Daniel, Noguera‐Morel, Lucero, Hernández‐Martín, Angela, Huerta‐Aragonés, Jorge, Torrelo, Antonio
Format: Artikel
Sprache:eng
Schlagworte:
Case reports
Children
drug reaction
Drug therapy
Hair
hair disorders
Hypertrichosis
Omeprazole
Pediatrics
Prostaglandin D2
Prostaglandin E2
Prostaglandins
Side effects
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Zusammenfassung:Omeprazole significantly increases duodenal prostaglandin E2 synthesis. Prostaglandins are involved in hair growth regulation: prostaglandin E2 and prostaglandin F2 alpha stimulate hair growth, and prostaglandin D2 has an inhibitory effect. The use of omeprazole can cause acquired generalized hypertrichosis by increasing prostaglandin E2 levels.
ISSN:0736-8046
1525-1470
DOI:10.1111/pde.13496