Risk Factors for Poststroke Cognitive Decline: The REGARDS Study (Reasons for Geographic and Racial Differences in Stroke)

BACKGROUND AND PURPOSE—Poststroke cognitive decline causes disability. Risk factors for poststroke cognitive decline independent of survivors’ prestroke cognitive trajectories are uncertain. METHODS—Among 22 875 participants aged ≥45 years without baseline cognitive impairment from the REGARDS cohor...

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Veröffentlicht in:	Stroke (1970) 2018-04, Vol.49 (4), p.987-994
Hauptverfasser:	Levine, Deborah A, Wadley, Virginia G, Langa, Kenneth M, Unverzagt, Frederick W, Kabeto, Mohammed U, Giordani, Bruno, Howard, George, Howard, Virginia J, Cushman, Mary, Judd, Suzanne E, Galecki, Andrzej T
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Black or African American Cognitive Dysfunction - epidemiology Cognitive Dysfunction - ethnology Cognitive Dysfunction - psychology Executive Function Female Geography Humans Incidence Intracranial Embolism - epidemiology Intracranial Embolism - psychology Learning Male Memory Middle Aged Risk Factors Stroke - epidemiology Stroke - psychology Survivors White People
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Zusammenfassung:	BACKGROUND AND PURPOSE—Poststroke cognitive decline causes disability. Risk factors for poststroke cognitive decline independent of survivors’ prestroke cognitive trajectories are uncertain. METHODS—Among 22 875 participants aged ≥45 years without baseline cognitive impairment from the REGARDS cohort (Reasons for Geographic and Racial Differences in Stroke), enrolled from 2003 to 2007 and followed through September 2015, we measured the effect of incident stroke (n=694) on changes in cognitive functions and cognitive impairment (Six-Item Screener score
ISSN:	0039-2499 1524-4628
DOI:	10.1161/STROKEAHA.117.018529