Are haplotypes in a single methotrexate pathway more predictive for response in rheumatoid arthritis than in different pathways?

Are haplotypes in a single methotrexate pathway more predictive for response in rheumatoid arthritis than in different pathways?

Letter to the editor with respect to: Lima A, Bernardes M, Azevedo R, Seabra V and Medeiros R. Moving toward personalized medicine in rheumatoid arthritis: SNPs in methotrexate intracellular pathways are associated with methotrexate therapeutic outcome. 17(15), 1649-1674 (2016).

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Bibliographische Detailangaben
Veröffentlicht in:Pharmacogenomics 2018-04, Vol.19 (5), p.379-381
Hauptverfasser: Soukup, Tomas, Barvik, Ivan, Nekvindova, Jana, Veleta, Tomas, Kubena, Ales A, Duintjer Tebbens, Jurjen, Pavek, Petr, Dosedel, Martin
Format: Artikel
Sprache:eng
Schlagworte:
Adenosine
Enzymes
Genes
Haplotypes
Methotrexate
personalized medicine
Pharmacogenomics
polymorphisms
Precision medicine
response
Rheumatoid arthritis
Studies
Vitamin B
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Zusammenfassung:Letter to the editor with respect to: Lima A, Bernardes M, Azevedo R, Seabra V and Medeiros R. Moving toward personalized medicine in rheumatoid arthritis: SNPs in methotrexate intracellular pathways are associated with methotrexate therapeutic outcome. 17(15), 1649-1674 (2016).
ISSN:1462-2416
1744-8042
DOI:10.2217/pgs-2016-0182