Immunology of oligodendrocyte precursor cells in vivo and in vitro

Remyelination following myelin/oligodendrocyte injury in the central nervous system (CNS) is dependent on oligodendrocyte progenitor cells (OPCs) migrating into lesion sites, differentiating into myelinating oligodendrocytes (OLs), and ensheathing axons. Experimental models indicate that robust OPC-...

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Veröffentlicht in:	Journal of neuroimmunology 2019-06, Vol.331, p.28-35
Hauptverfasser:	Antel, Jack P., Lin, Yun Hsuan, Cui, Qiao-Ling, Pernin, Florian, Kennedy, Timothy E., Ludwin, Samuel K., Healy, Luke M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive Immunity Adult Animals Antigens, Differentiation - analysis Brain - cytology Cell Differentiation Cells, Cultured Experimental autoimmune encephalomyelitis Glucose - pharmacology Humans Immunity, Innate Immunotherapy Mice Multiple sclerosis Multiple Sclerosis - pathology Multiple Sclerosis - therapy Myelin Nerve Tissue Proteins - analysis Neuroimmunomodulation Oligodendrocyte precursor cell Oligodendrocyte Precursor Cells - cytology Oligodendrocyte Precursor Cells - drug effects Oligodendrocyte Precursor Cells - immunology Oligodendrocyte Precursor Cells - physiology Oligodendroglia - cytology Rats Remyelination Remyelination - physiology
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