A 3D-printed flow distributor with uniform flow rate control for multi-stacked microfluidic systems
In the scale-up of chemical production in a microfluidic system, it is challenging to prevent flow maldistribution from a single inlet into stacked multiple microchannel exits. In the present study, a compact flow distributor equipped with a fluidic damper is developed by computational fluid dynamic...
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| Veröffentlicht in: | Lab on a chip 2018-01, Vol.18 (8), p.1250-1258 |
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| container_title | Lab on a chip |
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| creator | Park, Young-June Yu, Taejong Yim, Se-Jun You, Donghyun Kim, Dong-Pyo |
| description | In the scale-up of chemical production in a microfluidic system, it is challenging to prevent flow maldistribution from a single inlet into stacked multiple microchannel exits. In the present study, a compact flow distributor equipped with a fluidic damper is developed by computational fluid dynamics (CFD) along with experimental validation. A microfluidic flow distributor, which is equipped with an optimized fluidic damper and consists of 25 exit channels, is fabricated as an integrated body using a digital light processing (DLP) type 3D printer. The 3D printed flow distributor with a CFD-optimized fluidic damper is found to achieve a low maldistribution factor (MF) of 2.2% for the average flow rate over 25 exit channels while inducing only a minor increment ( |
| doi_str_mv | 10.1039/c8lc00004b |
| format | Article |
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In the present study, a compact flow distributor equipped with a fluidic damper is developed by computational fluid dynamics (CFD) along with experimental validation. A microfluidic flow distributor, which is equipped with an optimized fluidic damper and consists of 25 exit channels, is fabricated as an integrated body using a digital light processing (DLP) type 3D printer. The 3D printed flow distributor with a CFD-optimized fluidic damper is found to achieve a low maldistribution factor (MF) of 2.2% for the average flow rate over 25 exit channels while inducing only a minor increment (<6%) in the pressure drop. A generalized manual is proposed for the design of optimal flow distributors with different scale-up dimensions. Using the manual, an optimal flow distributor with 625 stacked microchannels with a MF of only 1.2% is successfully designed. 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It is expected that the design manual and the rapid printing platform will allow the efficient development of multi-channel stacked micro-devices such as those in drug delivery and energy conversion systems where equidistribution of fluid flow is highly demanded.</description><subject>Channels</subject><subject>Computational fluid dynamics</subject><subject>Distributors</subject><subject>Drug delivery systems</subject><subject>Energy conversion</subject><subject>Flow velocity</subject><subject>Fluid flow</subject><subject>Microchannels</subject><subject>Pressure drop</subject><subject>Three dimensional flow</subject><subject>Three dimensional printing</subject><subject>Uniform flow</subject><issn>1473-0197</issn><issn>1473-0189</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNpdkMtOwzAQRS0EoqWw4QOQJTYIKeBHEsfLEp5SJTawjhzHFi5JXPxQ1b_H0NIFs5mRfXQ1cwA4x-gGI8pvZdVLlCpvD8AU54xmCFf8cD9zNgEn3i8RwkVeVsdgQnhR8rJkUyDnkN5nK2fGoDqoe7uGnfHBmTYG6-DahA8YR6OtG7a_TgQFpR2Dsz1Mz3CIfTCZD0J-poTBSGd1H01nJPQbH9TgT8GRFr1XZ7s-A--PD2_1c7Z4fXqp54tM5jgPmcJESa5FJVqEqGCt0ioXSBaSC0EIZlVZCcYJx4Iz3rFOKVF0XHORc0qRpjNwtc1dOfsVlQ_NYLxUfS9GZaNvSNKCUhAuE3r5D13a6Ma0XaJISSgrOEnU9ZZKN3nvlG6SqEG4TYNR86O-qatF_av-LsEXu8jYDqrbo3-u6TfRFX-O</recordid><startdate>20180101</startdate><enddate>20180101</enddate><creator>Park, Young-June</creator><creator>Yu, Taejong</creator><creator>Yim, Se-Jun</creator><creator>You, Donghyun</creator><creator>Kim, Dong-Pyo</creator><general>Royal Society of Chemistry</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SP</scope><scope>7TB</scope><scope>7U5</scope><scope>8FD</scope><scope>FR3</scope><scope>L7M</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-6804-1955</orcidid><orcidid>https://orcid.org/0000-0003-4383-3056</orcidid></search><sort><creationdate>20180101</creationdate><title>A 3D-printed flow distributor with uniform flow rate control for multi-stacked microfluidic systems</title><author>Park, Young-June ; Yu, Taejong ; Yim, Se-Jun ; You, Donghyun ; Kim, Dong-Pyo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-e12ec9fa8ab003a7befe4a0c5c9aa2217868a79291a979d7deea5d9f9a49330f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Channels</topic><topic>Computational fluid dynamics</topic><topic>Distributors</topic><topic>Drug delivery systems</topic><topic>Energy conversion</topic><topic>Flow velocity</topic><topic>Fluid flow</topic><topic>Microchannels</topic><topic>Pressure drop</topic><topic>Three dimensional flow</topic><topic>Three dimensional printing</topic><topic>Uniform flow</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Young-June</creatorcontrib><creatorcontrib>Yu, Taejong</creatorcontrib><creatorcontrib>Yim, Se-Jun</creatorcontrib><creatorcontrib>You, Donghyun</creatorcontrib><creatorcontrib>Kim, Dong-Pyo</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Electronics & Communications Abstracts</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Lab on a chip</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Young-June</au><au>Yu, Taejong</au><au>Yim, Se-Jun</au><au>You, Donghyun</au><au>Kim, Dong-Pyo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A 3D-printed flow distributor with uniform flow rate control for multi-stacked microfluidic systems</atitle><jtitle>Lab on a chip</jtitle><addtitle>Lab Chip</addtitle><date>2018-01-01</date><risdate>2018</risdate><volume>18</volume><issue>8</issue><spage>1250</spage><epage>1258</epage><pages>1250-1258</pages><issn>1473-0197</issn><eissn>1473-0189</eissn><abstract>In the scale-up of chemical production in a microfluidic system, it is challenging to prevent flow maldistribution from a single inlet into stacked multiple microchannel exits. In the present study, a compact flow distributor equipped with a fluidic damper is developed by computational fluid dynamics (CFD) along with experimental validation. A microfluidic flow distributor, which is equipped with an optimized fluidic damper and consists of 25 exit channels, is fabricated as an integrated body using a digital light processing (DLP) type 3D printer. The 3D printed flow distributor with a CFD-optimized fluidic damper is found to achieve a low maldistribution factor (MF) of 2.2% for the average flow rate over 25 exit channels while inducing only a minor increment (<6%) in the pressure drop. A generalized manual is proposed for the design of optimal flow distributors with different scale-up dimensions. Using the manual, an optimal flow distributor with 625 stacked microchannels with a MF of only 1.2% is successfully designed. It is expected that the design manual and the rapid printing platform will allow the efficient development of multi-channel stacked micro-devices such as those in drug delivery and energy conversion systems where equidistribution of fluid flow is highly demanded.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>29569667</pmid><doi>10.1039/c8lc00004b</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-6804-1955</orcidid><orcidid>https://orcid.org/0000-0003-4383-3056</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1473-0197 |
| ispartof | Lab on a chip, 2018-01, Vol.18 (8), p.1250-1258 |
| issn | 1473-0197 1473-0189 |
| language | eng |
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| source | Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
| subjects | Channels Computational fluid dynamics Distributors Drug delivery systems Energy conversion Flow velocity Fluid flow Microchannels Pressure drop Three dimensional flow Three dimensional printing Uniform flow |
| title | A 3D-printed flow distributor with uniform flow rate control for multi-stacked microfluidic systems |
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