A Randomized Trial of High-Flow Oxygen Therapy in Infants with Bronchiolitis

A Randomized Trial of High-Flow Oxygen Therapy in Infants with Bronchiolitis

In a multicenter, randomized, controlled trial, infants with bronchiolitis needing oxygen therapy received high-flow or standard-flow oxygen. High flow resulted in significantly lower escalation and treatment-failure rates than standard oxygen therapy.

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Bibliographische Detailangaben
Veröffentlicht in:The New England journal of medicine 2018-03, Vol.378 (12), p.1121-1131
Hauptverfasser: Franklin, Donna, Babl, Franz E, Schlapbach, Luregn J, Oakley, Ed, Craig, Simon, Neutze, Jocelyn, Furyk, Jeremy, Fraser, John F, Jones, Mark, Whitty, Jennifer A, Dalziel, Stuart R, Schibler, Andreas
Format: Artikel
Sprache:eng
Schlagworte:
Airway management
Bronchopneumonia
Children & youth
Childrens health
Clinical trials
Consent
Critical care
Evidence-based medicine
Hospital costs
Hypoxemia
Infants
Intensive care
Intensive care units
Intervention
Intubation
Medical ethics
Medical research
Oxygen
Oxygen therapy
Pediatrics
Pneumothorax
Respiratory therapy
Tachycardia
Weaning
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Beschreibung
Zusammenfassung:In a multicenter, randomized, controlled trial, infants with bronchiolitis needing oxygen therapy received high-flow or standard-flow oxygen. High flow resulted in significantly lower escalation and treatment-failure rates than standard oxygen therapy.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa1714855