Microscopic hematuria is a risk factor of incident chronic kidney disease in the Korean general population: a community-based prospective cohort study

Abstract Background Although asymptomatic microscopic hematuria (MH) is a common finding in clinical practice, its long-term outcome remains unknown. Aim This study evaluated the clinical implication of MH in the general population using a large-scale long-term longitudinal cohort database. Methods...

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Veröffentlicht in:	QJM : An International Journal of Medicine 2018-06, Vol.111 (6), p.389-397
Hauptverfasser:	Kim, H, Lee, M, Cha, M -U, Nam, K H, An, S Y, Park, S, Jhee, J H, Yun, H -R, Kee, Y K, Park, J T, Yoo, T -H, Kang, S -W, Han, S H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Disease Progression Female Glomerular Filtration Rate Hematuria - complications Hematuria - epidemiology Humans Incidence Korea - epidemiology Male Middle Aged Multivariate Analysis Propensity Score Proportional Hazards Models Prospective Studies Proteinuria - complications Renal Insufficiency, Chronic - complications Renal Insufficiency, Chronic - epidemiology Risk Factors Urinalysis
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Zusammenfassung:	Abstract Background Although asymptomatic microscopic hematuria (MH) is a common finding in clinical practice, its long-term outcome remains unknown. Aim This study evaluated the clinical implication of MH in the general population using a large-scale long-term longitudinal cohort database. Methods This study included 8719 participants from the Korean Genome and Epidemiology Study between 2001 and 2014. MH was defined as ≥5 red blood cells per high-power field in random urinalysis without evidence of pyuria. The primary study outcome measure was incident chronic kidney disease (CKD), defined as estimated glomerular filtration rate
ISSN:	1460-2725 1460-2393
DOI:	10.1093/qjmed/hcy054