Phytochemical-assisted synthetic approaches for silver nanoparticles antimicrobial applications: A review

Silver nanoparticles (Ag NPs) have recently emerged as promising materials in the biomedical sciences because of their antimicrobial activities towards a wide variety of microorganisms. Nanomaterial-based drug delivery systems with antimicrobial activity are critical as they may lead to novel treatments for cutaneous pathogens. In this review, we explore the recent progress on phytochemical-mediated synthesis of Ag NPs for antimicrobial treatment and associated infectious diseases. We discuss the biological activity of Ag NPs including mechanisms, antimicrobial activity, and antifungal/antiviral effects towards various microorganisms. The advent of Ag NP-based nanocarriers and nano-vehicles is also described for treatment of different diseases, along with the mechanisms of microbial inhibition. Overall, this review will provide a rational vision of the main achievements of Ag NPs as nanocarriers for inhibition of various microbial agents (bacteria, fungus, and virus). [Display omitted] •Reviewed the phytochemicals-mediated synthesis of Ag NPs for microbial activity•Phytochemicals-Ag NPs showed antibacterial activity against wide spectrum of bacteria.•Antibacterial mechanism and role of Ag+ ion is discussed.•Antifungal and antiviral activities of Ag NPs are summarized.