Impact of Body Weight Loss From Maximum Weight on Fragility Bone Fractures in Japanese Patients With Type 2 Diabetes: The Fukuoka Diabetes Registry

Impact of Body Weight Loss From Maximum Weight on Fragility Bone Fractures in Japanese Patients With Type 2 Diabetes: The Fukuoka Diabetes Registry

There is growing evidence that weight loss is associated with increased fracture risk in the general population. As patients with diabetes often lose weight intentionally or unintentionally, we aimed to investigate prospectively the relationship between weight loss from maximum body weight and fract...

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Veröffentlicht in:Diabetes care 2018-05, Vol.41 (5), p.1061-1067
Hauptverfasser: Komorita, Yuji, Iwase, Masanori, Fujii, Hiroki, Ohkuma, Toshiaki, Ide, Hitoshi, Jodai-Kitamura, Tamaki, Sumi, Akiko, Yoshinari, Masahito, Nakamura, Udai, Kang, Dongchon, Kitazono, Takanari
Format: Artikel
Sprache:eng
Schlagworte:
Body weight
Body weight loss
Bones
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Fractures
Fragility
Hip
Impact analysis
Men
Patients
Post-menopause
Research design
Risk analysis
Risk factors
Spine
Weight control
Weight loss
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Zusammenfassung:There is growing evidence that weight loss is associated with increased fracture risk in the general population. As patients with diabetes often lose weight intentionally or unintentionally, we aimed to investigate prospectively the relationship between weight loss from maximum body weight and fracture risk. A total of 4,706 Japanese participants with type 2 diabetes (mean age 66 years), including 2,755 men and 1,951 postmenopausal women, were followed for a median of 5.3 years and were divided according to weight loss from maximum weight:
ISSN:0149-5992
1935-5548
DOI:10.2337/dc17-2004