Paracetamol Serum Concentrations in Neonates Treated Enterally for Ductal Closure: A Pilot Study

We determined serum paracetamol concentrations 4 hours after the eighth dose in infants treated enterally for ductal closure. Serum paracetamol concentrations correlated (P = .0026) with ductal response. No patent ductus arteriosus in a baby with paracetamol levels

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Bibliographische Detailangaben
Veröffentlicht in:	The Journal of pediatrics 2018-07, Vol.198, p.304-307
Hauptverfasser:	Bin-Nun, Alona, Fink, Daniel, Mimouni, Francis B., Algur, Nurit, Hammerman, Cathy
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen - blood Acetaminophen - therapeutic use Administration, Oral Analgesics, Non-Narcotic - blood Analgesics, Non-Narcotic - therapeutic use Ductus Arteriosus, Patent - blood Ductus Arteriosus, Patent - drug therapy Humans Infant, Newborn Infant, Premature Infant, Premature, Diseases - blood Infant, Premature, Diseases - drug therapy paracetamol patent ductus arteriosus Pilot Projects Retrospective Studies Transaminases - blood Treatment Outcome
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Beschreibung
Zusammenfassung:	We determined serum paracetamol concentrations 4 hours after the eighth dose in infants treated enterally for ductal closure. Serum paracetamol concentrations correlated (P = .0026) with ductal response. No patent ductus arteriosus in a baby with paracetamol levels
ISSN:	0022-3476 1097-6833
DOI:	10.1016/j.jpeds.2018.01.024