In Situ Observation of Spherical DNA Assembly “Nucleo-cages” in Water and Their Stabilization by Photocrosslinking
Formation of spherical microstructures from three-way junction DNA is observed in water by confocal laser scanning fluorescence microscopy (CLSM). Photocrosslinking of nucleo-cages by psoralen derivatives is shown to effectively increase their stability against heat and urea.
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| Veröffentlicht in: | Chemistry letters 2006-05, Vol.35 (5), p.486-487 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Formation of spherical microstructures from three-way junction DNA is observed in water by confocal laser scanning fluorescence microscopy (CLSM). Photocrosslinking of nucleo-cages by psoralen derivatives is shown to effectively increase their stability against heat and urea. |
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| ISSN: | 0366-7022 1348-0715 |
| DOI: | 10.1246/cl.2006.486 |