Cigarette smoking and glutathione S-transferase M1 polymorphism associated with risk for uterine cervical cancer

Aim: To elucidate the role of tobacco smoking and polymorphisms of carcinogen metabolism genes in cervical carcinogenesis. Methods: We analyzed genotypes of nine genes, 11 polymorphisms encoding carcinogen metabolizing enzymes, information on smoking, and the presence of human papillomavirus in 12...

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Veröffentlicht in:	The journal of obstetrics and gynaecology research 2008-12, Vol.34 (6), p.994-1001
Hauptverfasser:	Nishino, Koji, Sekine, Masayuki, Kodama, Shoji, Sudo, Norihito, Aoki, Yoichi, Seki, Nao, Tanaka, Kenichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cocarcinogenesis Female glutathione S-transferase M1 Glutathione Transferase - genetics human papilloma virus Human papillomavirus Humans Middle Aged Neoplasms, Squamous Cell - enzymology Neoplasms, Squamous Cell - etiology Neoplasms, Squamous Cell - genetics Neoplasms, Squamous Cell - virology Papillomaviridae - growth & development Papillomavirus Infections - virology polymorphism Polymorphism, Genetic smoking Smoking - adverse effects Smoking - genetics uterine cervical cancer Uterine Cervical Neoplasms - enzymology Uterine Cervical Neoplasms - etiology Uterine Cervical Neoplasms - genetics Uterine Cervical Neoplasms - virology
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