The Influence of Ruptured Scar Pattern on the Healing Potential of Anterior Cruciate Ligament Remnant Cells

Background: Vascular CD34+ cells in anterior cruciate ligament (ACL) tissues have a potential for high proliferation and multilineage differentiation, which can accelerate tendon-bone healing after ACL reconstruction. To predict outcomes of ACL reconstruction with remnant preservation or ruptured ti...

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Veröffentlicht in:	The American journal of sports medicine 2018-05, Vol.46 (6), p.1382-1388
Hauptverfasser:	Kirizuki, Shinsuke, Matsumoto, Tomoyuki, Ueha, Takeshi, Uefuji, Atsuo, Inokuchi, Takao, Takayama, Koji, Hashimoto, Shingo, Hayashi, Shinya, Matsushita, Takehiko, Kuroda, Ryosuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anterior Cruciate Ligament - pathology Anterior Cruciate Ligament - physiopathology Anterior Cruciate Ligament - surgery Anterior Cruciate Ligament Injuries - physiopathology Anterior Cruciate Ligament Injuries - surgery Anterior Cruciate Ligament Reconstruction CD4 Lymphocyte Count Cell Differentiation Cell Proliferation Cicatrix - pathology Cicatrix - physiopathology Endothelial Cells - physiology Female Humans Knee Male Osteogenesis Sports medicine Tendons - physiology Wound Healing - physiology Young Adult
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Zusammenfassung:	Background: Vascular CD34+ cells in anterior cruciate ligament (ACL) tissues have a potential for high proliferation and multilineage differentiation, which can accelerate tendon-bone healing after ACL reconstruction. To predict outcomes of ACL reconstruction with remnant preservation or ruptured tissue incorporation, patient characteristics should be considered. However, the influence of ACL remnant morphologic pattern on healing potential remains unknown. Hypothesis: The healing potential of ACL remnants could differ among their morphologic patterns. Study Design: Descriptive laboratory study. Methods: ACL remnant tissues were harvested from patients aged
ISSN:	0363-5465 1552-3365
DOI:	10.1177/0363546518755753