Wavelength‐dependent scattering in human eye with cataracts

The gradual process in which the crystalline lens is cloudy due to the appearance of elements giving rise to variations in the refractive index is known as cataract. Clinical assessment is usually complicated because it considers patient's perception, and individuals with similar development ha...

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Veröffentlicht in:Journal of biophotonics 2018-08, Vol.11 (8), p.e201700235-n/a
Hauptverfasser: Kelly‐Pérez, Ismael, Méndez‐Aguilar, Emilia M., Treviño‐Palacios, Carlos G., Bruce, Neil C., Berriel‐Valdos, Luis R., Al‐Hohamedi, Haroun, Bende, Thomas
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Sprache:eng
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Zusammenfassung:The gradual process in which the crystalline lens is cloudy due to the appearance of elements giving rise to variations in the refractive index is known as cataract. Clinical assessment is usually complicated because it considers patient's perception, and individuals with similar development have different visual deficits. This work presents a model which considers the fluctuations in the refractive index as spherical particles produce measurable scatter radial profiles patterns on the retina. Measurements for 2 different wavelengths simultaneously provide information on particle size and a quantitative assessment by measurement of the fluctuations of the refractive index. Early cataract formation is foretold by comparing scattering radial profiles light pattern distributions reflected upon the retina at 2 different wavelengths. The computational model developed presents wavelength‐dependent scattering distributions with angular crossovers in them. We obtained that the crossover angular point is inversely proportional to the size of the particle distributions associated with the nucleation precursor of eye cataracts.
ISSN:1864-063X
1864-0648
DOI:10.1002/jbio.201700235