Estimates of Within-Person Biological Variation and Reference Change Values of Serum S100B and NSE Proteins

[...]time course studies indicated that participants' test values returned to baseline within 48 h (data not shown). [...]we were able to model 1 event as casecontrol design because 4 subjects had their scheduled fights canceled on the day of the event but provided blood samples (i.e., controls). The Department of Clinical Laboratory Science Upstate Medical University 750 East Adams Street, WH 3260-B Syracuse, NY 13210 Fax 315-464-4609 E-mail johnspau@upstate.edu Previously published online at DOI:10.1373/clinchem.2017.285973 1 Nonstandard abbreviations: BV, biological variation; S100B, S100-ß protein; NSE, neuron-specific enolase; CVI, within-person BV; RCV, reference change value; CVG, between-person BV; CVA,analytical imprecision.