Reducing betaglycan expression by RNA interference (RNAi) attenuates inhibin bioactivity in LβT2 gonadotropes

Betaglycan is an inhibin-binding protein co-receptor, the forced expression of which confers inhibin responsiveness on cells previously non-responsive to inhibin. The present study determines whether removal of betaglycan expression in otherwise inhibin-responsive cells will render the cells insensi...

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Veröffentlicht in:	Molecular and cellular endocrinology 2009-08, Vol.307 (1-2), p.149-156
Hauptverfasser:	Escalona, Ruth M., Stenvers, Kaye L., Farnworth, Paul G., Findlay, Jock K., Ooi, Guck T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Betaglycan FSH Inhibin LβT2 Pituitary cells siRNA
Online-Zugang:	Volltext
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