Tissue autoantibodies and rheumatoid factor in the chronic hepatitis C virus infection

Tissue autoantibodies and rheumatoid factor in the chronic hepatitis C virus infection

The aim of this study was to determine the prevalence of tissue autoantibodies and rheumatoid factor (RF) in patients with chronic hepatitis C virus (HCV) infection and their relationship with viral genotype and antiviral treatment. This study included 21 patients infected with HCV and 24 healthy su...

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Veröffentlicht in:Acta bioquímica clínica latinoamericana 2009-03, Vol.42 (1), p.11-16
Hauptverfasser: Caula, Cinthya, Pieri, Elsa, Cooke, Paula
Format: Artikel
Sprache:eng
Schlagworte:
Hepatitis C virus
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Zusammenfassung:The aim of this study was to determine the prevalence of tissue autoantibodies and rheumatoid factor (RF) in patients with chronic hepatitis C virus (HCV) infection and their relationship with viral genotype and antiviral treatment. This study included 21 patients infected with HCV and 24 healthy subjects. Anti-nuclear (ANA), anti-smooth muscle (SMA), anti-mitochondrial (AMA) and anti-liver-kidney microsomal-1 (LKM-1) autoantibodies were investigated by indirect immunofluorescence technique, and RF by latex agglutination. ANA were found in 43% of the patients with HCV infection and 4% of the controls (p
ISSN:0325-2957