Effects of Illicit Drug Use on Adherence to Prescribed Antiretroviral Medication

This exploratory analysis compared adherence to antiretroviral medication on days that illicit drugs were used and on matched abstinence days in twelve subjects who used MEMS caps during participation in a clinical trial. Adherence on drug use days was lower in seven subjects, higher in one, and the...

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Veröffentlicht in:	The American journal on addictions 2003-10, Vol.12 (5), p.455-458
Hauptverfasser:	Rosen, Marc I., Rigsby, Michael O., Dieckhaus, Kevin D., Cramer, Joyce A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-HIV Agents - administration & dosage Comorbidity Counseling Feedback HIV Infections - drug therapy HIV Infections - epidemiology HIV Infections - psychology Humans Male Street Drugs Substance-Related Disorders - diagnosis Substance-Related Disorders - epidemiology Substance-Related Disorders - psychology Token Economy Treatment Outcome Treatment Refusal - psychology Treatment Refusal - statistics & numerical data
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Beschreibung
Zusammenfassung:	This exploratory analysis compared adherence to antiretroviral medication on days that illicit drugs were used and on matched abstinence days in twelve subjects who used MEMS caps during participation in a clinical trial. Adherence on drug use days was lower in seven subjects, higher in one, and the same in four. Three subjects maintained 100% adherence despite illicit substance use on studied days. Thus, in a subset of patients, the actions involved in procuring drugs and the acute effects of using them contribute to non-adherence on those specific drug use days, associated with substance abuse. (Am J Addict 2003;12:455-458)
ISSN:	1055-0496 1521-0391
DOI:	10.1080/10550490390240828