Cytokine gene polymorphism in denture stomatitis patients: A clinical study

Objective This clinical study investigated the association between cytokine gene polymorphism and Candida growth in denture stomatitis (DS) patients. Subjects and Methods Saliva and blood samples of 160 complete denture wearers (80 healthy controls and 80 with DS) were collected for mycological and...

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Veröffentlicht in:	Oral diseases 2018-09, Vol.24 (6), p.983-992
Hauptverfasser:	Keşoğlu, AC, Bural, C, Genç, GE, Erturan, Z, Çınar Kekik, Ç, Oğuz, F, Bilgin, T, Bilhan, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Candida Candida albicans Candida albicans - growth & development Candida glabrata - growth & development Case-Control Studies Colonies Colony Count, Microbial cytokine cytokine gene polymorphism Cytokines Cytokines - genetics Data processing Dentistry denture stomatitis Dentures - adverse effects Female Gene polymorphism Haplotypes Humans Interleukin-10 - genetics Interleukin-6 - genetics Male Middle Aged Polymorphism, Genetic Saliva Saliva - microbiology Stomatitis Stomatitis - etiology Stomatitis - genetics Stomatitis - microbiology Transforming Growth Factor beta - genetics Tumor Necrosis Factor-alpha - genetics
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Zusammenfassung:	Objective This clinical study investigated the association between cytokine gene polymorphism and Candida growth in denture stomatitis (DS) patients. Subjects and Methods Saliva and blood samples of 160 complete denture wearers (80 healthy controls and 80 with DS) were collected for mycological and gene polymorphism testing, respectively. Salivary Candida growth and TNF‐α, TGF‐β, IL‐6, and IL‐10 genotypes were investigated. Data were analyzed using Student’s t test, Mann–Whitney U test, chi‐square analysis, and continuity (yates) correction tests (p
ISSN:	1354-523X 1601-0825
DOI:	10.1111/odi.12844