Clerodens E–J, antibacterial caffeic acid derivatives from the aerial part of Clerodendranthus spicatus
Six new caffeic acid derivatives, Clerodens E–J (1–6) were isolated from the aerial part of Clerodendranthus spicatus. Their structures were elucidated by extensive spectroscopic analysis, including NMR, MS, and ECD data. Compound 1 showed moderate antibacterial activities against drug-resistant str...
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| Veröffentlicht in: | Fitoterapia 2016-10, Vol.114, p.110-114 |
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| container_end_page | 114 |
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| container_title | Fitoterapia |
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| creator | Li, Qing He, Ying-Na Shi, Xiao-Wei Kang, Li-Ying Niu, Li-Ying Wang, Xin-Guo Feng, Wei |
| description | Six new caffeic acid derivatives, Clerodens E–J (1–6) were isolated from the aerial part of Clerodendranthus spicatus. Their structures were elucidated by extensive spectroscopic analysis, including NMR, MS, and ECD data. Compound 1 showed moderate antibacterial activities against drug-resistant strains of bacteria in vitro.
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| doi_str_mv | 10.1016/j.fitote.2016.08.021 |
| format | Article |
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[Display omitted]</description><subject>aerial parts</subject><subject>Anti-Bacterial Agents - chemistry</subject><subject>Anti-Bacterial Agents - isolation & purification</subject><subject>antibacterial properties</subject><subject>bacteria</subject><subject>Bacteria - drug effects</subject><subject>caffeic acid</subject><subject>Caffeic acid derivatives</subject><subject>Caffeic Acids - chemistry</subject><subject>Caffeic Acids - isolation & purification</subject><subject>Clerodendranthus spicatus</subject><subject>Clerodens E–J</subject><subject>drug resistance</subject><subject>Drug Resistance, Bacterial</subject><subject>Lamiaceae - chemistry</subject><subject>medicinal plants</subject><subject>Microbial Sensitivity Tests</subject><subject>Molecular Structure</subject><subject>nuclear magnetic resonance spectroscopy</subject><subject>Orthosiphon aristatus</subject><subject>Plant Components, Aerial - chemistry</subject><issn>0367-326X</issn><issn>1873-6971</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1q3DAQx0VJabZJ36AUHXOI3dGHrfUlEJb0i0AvLeQmxtKIaPGut5K8kFvfIW_YJ6mDkx57Gmb4zX-YH2PvBdQCRPtxW4dYxkK1nLsa1jVI8YqtxNqoqu2MOGErUK2plGzvTtnbnLcAolFavGGn0jSd0rpdsbgZKI2e9pnf_Pn9-O2S477EHl2hFHHgDkOg6Di66LmfZ0cs8UiZhzTueLknjgt4wFT4GPhLnk9z0P2UeT5Eh2XK5-x1wCHTu-d6xn5-uvmx-VLdfv_8dXN9WznVNaVyjW5Ak1fYdYBGdSFAoNAYJanzJHtQRvY9Qi90awiVN7IVvaQGzVqTVmfsYsk9pPHXRLnYXcyOhgH3NE7ZSgBQAkC3M6oX1KUx50TBHlLcYXqwAuyTZLu1i2T7JNnC2s6S57UPzxemfkf-39KL1Rm4WgCa_zxGSja7SHtHPiZyxfox_v_CX8Tckco</recordid><startdate>201610</startdate><enddate>201610</enddate><creator>Li, Qing</creator><creator>He, Ying-Na</creator><creator>Shi, Xiao-Wei</creator><creator>Kang, Li-Ying</creator><creator>Niu, Li-Ying</creator><creator>Wang, Xin-Guo</creator><creator>Feng, Wei</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7S9</scope><scope>L.6</scope></search><sort><creationdate>201610</creationdate><title>Clerodens E–J, antibacterial caffeic acid derivatives from the aerial part of Clerodendranthus spicatus</title><author>Li, Qing ; He, Ying-Na ; Shi, Xiao-Wei ; Kang, Li-Ying ; Niu, Li-Ying ; Wang, Xin-Guo ; Feng, Wei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c395t-c54504ed3a990a739ff0fef5732e9de2b0372bba0b1467ea3d7261b2e5a784e43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>aerial parts</topic><topic>Anti-Bacterial Agents - chemistry</topic><topic>Anti-Bacterial Agents - isolation & purification</topic><topic>antibacterial properties</topic><topic>bacteria</topic><topic>Bacteria - drug effects</topic><topic>caffeic acid</topic><topic>Caffeic acid derivatives</topic><topic>Caffeic Acids - chemistry</topic><topic>Caffeic Acids - isolation & purification</topic><topic>Clerodendranthus spicatus</topic><topic>Clerodens E–J</topic><topic>drug resistance</topic><topic>Drug Resistance, Bacterial</topic><topic>Lamiaceae - chemistry</topic><topic>medicinal plants</topic><topic>Microbial Sensitivity Tests</topic><topic>Molecular Structure</topic><topic>nuclear magnetic resonance spectroscopy</topic><topic>Orthosiphon aristatus</topic><topic>Plant Components, Aerial - chemistry</topic><toplevel>online_resources</toplevel><creatorcontrib>Li, Qing</creatorcontrib><creatorcontrib>He, Ying-Na</creatorcontrib><creatorcontrib>Shi, Xiao-Wei</creatorcontrib><creatorcontrib>Kang, Li-Ying</creatorcontrib><creatorcontrib>Niu, Li-Ying</creatorcontrib><creatorcontrib>Wang, Xin-Guo</creatorcontrib><creatorcontrib>Feng, Wei</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><jtitle>Fitoterapia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Qing</au><au>He, Ying-Na</au><au>Shi, Xiao-Wei</au><au>Kang, Li-Ying</au><au>Niu, Li-Ying</au><au>Wang, Xin-Guo</au><au>Feng, Wei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clerodens E–J, antibacterial caffeic acid derivatives from the aerial part of Clerodendranthus spicatus</atitle><jtitle>Fitoterapia</jtitle><addtitle>Fitoterapia</addtitle><date>2016-10</date><risdate>2016</risdate><volume>114</volume><spage>110</spage><epage>114</epage><pages>110-114</pages><issn>0367-326X</issn><eissn>1873-6971</eissn><abstract>Six new caffeic acid derivatives, Clerodens E–J (1–6) were isolated from the aerial part of Clerodendranthus spicatus. Their structures were elucidated by extensive spectroscopic analysis, including NMR, MS, and ECD data. Compound 1 showed moderate antibacterial activities against drug-resistant strains of bacteria in vitro.
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| ispartof | Fitoterapia, 2016-10, Vol.114, p.110-114 |
| issn | 0367-326X 1873-6971 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | aerial parts Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification antibacterial properties bacteria Bacteria - drug effects caffeic acid Caffeic acid derivatives Caffeic Acids - chemistry Caffeic Acids - isolation & purification Clerodendranthus spicatus Clerodens E–J drug resistance Drug Resistance, Bacterial Lamiaceae - chemistry medicinal plants Microbial Sensitivity Tests Molecular Structure nuclear magnetic resonance spectroscopy Orthosiphon aristatus Plant Components, Aerial - chemistry |
| title | Clerodens E–J, antibacterial caffeic acid derivatives from the aerial part of Clerodendranthus spicatus |
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