Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics

Highlights • The future of bone grafting materials lies in osteoinductive capabilities. • Bone requires a variety of important ions to maintain healthy functionality. • The addition of important ions to calcium phosphate (CaP) materials can have beneficial effects.

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Bibliographische Detailangaben
Veröffentlicht in:	Trends in biotechnology (Regular ed.) 2013-10, Vol.31 (10), p.594-605
Hauptverfasser:	Bose, Susmita, Fielding, Gary, Tarafder, Solaiman, Bandyopadhyay, Amit
Format:	Artikel
Sprache:	eng
Schlagworte:	Additives Angiogenesis Animals biocompatible materials Biocompatible Materials - chemistry Biological and medical sciences Biomaterials Biomedical materials Biotechnology Bone and Bones - blood supply bone formation Bone Remodeling bones Calcium Calcium phosphates Calcium Phosphates - chemistry Ceramics Copper dopants or trace metal ions Fundamental and applied biological sciences. Psychology Growth hormones Humans Internal Medicine ions Lithium Magnesium Manganese Metal ions Metals - chemistry Neovascularization, Physiologic - physiology osteogenesis Osteogenesis - drug effects Osteogenesis - physiology silicon Strontium Studies Tissue Engineering Trace elements Trace metals Vascular endothelial growth factor zinc
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Beschreibung
Zusammenfassung:	Highlights • The future of bone grafting materials lies in osteoinductive capabilities. • Bone requires a variety of important ions to maintain healthy functionality. • The addition of important ions to calcium phosphate (CaP) materials can have beneficial effects.
ISSN:	0167-7799 1879-3096
DOI:	10.1016/j.tibtech.2013.06.005