Management of neurosyphilis: time for a new approach?

Management of neurosyphilis: time for a new approach?

Given the long term sequelae of untreated neurosyphilis and insensitive tests to detect treponemes in the cerebrospinal fluid, questions regarding the utility of a lumbar puncture and cerebrospinal fluid analysis either to confirm or exclude neurosyphilis are raised.

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Bibliographische Detailangaben
Veröffentlicht in:Internal medicine journal 2018-02, Vol.48 (2), p.204-206
Hauptverfasser: Smibert, Olivia C., Jenney, Adam W. J., Spelman, Denis W.
Format: Artikel
Sprache:eng
Schlagworte:
Australasia - epidemiology
Cerebrospinal fluid
Complications
Diagnostic Tests, Routine - methods
Disease Management
Humans
Neurosyphilis
Neurosyphilis - diagnosis
Neurosyphilis - epidemiology
Neurosyphilis - therapy
rapid plasma reagin
syphilis
Syphilis Serodiagnosis - methods
syphilis serology
Time Factors
Treponema pallidum - isolation & purification
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Beschreibung
Zusammenfassung:Given the long term sequelae of untreated neurosyphilis and insensitive tests to detect treponemes in the cerebrospinal fluid, questions regarding the utility of a lumbar puncture and cerebrospinal fluid analysis either to confirm or exclude neurosyphilis are raised.
ISSN:1444-0903
1445-5994
DOI:10.1111/imj.13703