A polyanhydride-based implantable single dose vaccine platform for long-term immunity

A polyanhydride-based implantable single dose vaccine platform for long-term immunity

•Cyto-exclusive polyanhydride vaccine implant.•Collagen diffusion barrier for immune feedback design.•Limited surface area of polyanhydride hydrolysis for extended vaccine release.•3 stage single injection vaccine delivery device.

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Bibliographische Detailangaben
Veröffentlicht in:Vaccine 2018-02, Vol.36 (7), p.1024-1025
Hauptverfasser: Schaut, Robert G., Brewer, Matthew T., Mendoza, Kriscelle, Jackman, John, Narasimhan, Balaji, Jones, Douglas E.
Format: Artikel
Sprache:eng
Schlagworte:
Antigens
Immunity
Polyanhydrides
Transplants & implants
Vaccines
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Beschreibung
Zusammenfassung:•Cyto-exclusive polyanhydride vaccine implant.•Collagen diffusion barrier for immune feedback design.•Limited surface area of polyanhydride hydrolysis for extended vaccine release.•3 stage single injection vaccine delivery device.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2017.11.067