Oncological effect of palliative transurethral resection of the prostate in patients with advanced prostate cancer: a propensity score matching study

Purpose We investigated the oncologic effect of palliative transurethral resection of the prostate (pTURP) in patients with prostate cancer who received primary androgen deprivation therapy. Methods We reviewed 614 patients, including 83 who underwent pTURP; those with incidental prostate cancer wer...

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Veröffentlicht in:Journal of cancer research and clinical oncology 2018-04, Vol.144 (4), p.751-758
Hauptverfasser: Choi, Se Young, Ryu, Jeman, You, Dalsan, Jeong, In Gab, Hong, Jun Hyuk, Ahn, Hanjong, Kim, Choung-Soo
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Sprache:eng
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Zusammenfassung:Purpose We investigated the oncologic effect of palliative transurethral resection of the prostate (pTURP) in patients with prostate cancer who received primary androgen deprivation therapy. Methods We reviewed 614 patients, including 83 who underwent pTURP; those with incidental prostate cancer were excluded. Patients were divided into the TURP group and non-TURP group. Propensity score matching was performed for comorbidity, initial prostate-specific antigen (PSA), TNM stage, and Gleason score (GS). The Kaplan–Meier method was used to confirm castration-resistant prostate cancer (CRPC), cancer-specific survival (CSS), and overall survival (OS). Cox regression was performed to confirm factors affecting CSS. Results Before matching, the TURP group had a worse TNM stage ( p  
ISSN:0171-5216
1432-1335
DOI:10.1007/s00432-018-2597-5